Nicolas Cage

Speckles the Mole (voice)

Dee Bradley Baker

Mooch the Fly (voice)

Will Arnett

Kip Killian

Tracy Morgan

Blaster the Guinea Pig (voice)

Jon Favreau

Hurley the Guinea Pig (voice)

Zach Galifianakis

Ben

Steve Buscemi

Bucky the Hamster (voice)

Bill Nighy

Leonard Saber

Sam Rockwell

Darwin the Guinea Pig (voice)

Penélope Cruz

Juarez the Guinea Pig (voice)

Kelli Garner

Marcie

Jared Lavette

Jared the Skunk (voice)

Micah Lavette

Micah the Fox (voice)

Niecy Nash

Rosalita

Loudon Wainwright III

Grandpa Goodman

Tyler Patrick Jones

Connor

Piper Mackenzie Harris

Penny

Chris Ellis

NSA Director

Gabriel Casseus

Carter

Justin Mentell

Terrell

Troy Robinson

Agent

Travis Davis

Agent

Corey Michael Eubanks

Agent

Mini Anden

Saber's Assistant

Mike Stenson

Executive Producer

David P.I. James

Executive Producer

Duncan Henderson

Executive Producer

Chad Oman

Executive Producer

Hoyt Yeatman

Director