Jason O'Mara

Albert Wesker

Spencer Locke

K-Mart

Paul W. S. Anderson

Writer

Madeline Carroll

White Queen

Kirk B.R. Woller

Scientist

Martin Moszkowicz

Executive Producer

Mike Epps

L.J.

Brian Steele

Rancid / Tyrant

Milla Jovovich

Alice

Ali Larter

Claire Redfield

Iain Glen

Dr. Isaacs

Victor Hadida

Executive Producer

Oded Fehr

Carlos Olivera

Ashanti

Betty

Joe Hursley

Otto

Christopher Egan

Mikey

William Abadie

French Envoy

Matthew Marsden

Slater

Linden Ashby

Chaser

James Tumminia

Lab Tech

Valorie Hubbard

Ma

Carrie Eklund

Camp Survivor (uncredited)

John Eric Bentley

Umbrella Tech

Rick Cramer

Ice Hockey / Corridor Guard

Peter O'Meara

British Envoy

Ramón Franco

Runty

Shane Woodson

Piggy

Russell Mulcahy

Director

Kelly Van Horn

Executive Producer