Danny Trejo

Uncle Machete

Daryl Sabara

Juni Cortez

Jeremy Piven

Danger D'Amo / Tick Tock / Time Keeper

Antonio Banderas

Gregorio Cortez (uncredited)

Alexa PenaVega

Carmen Cortez

Ricky Gervais

Voice of Argonaut

Joel McHale

Wilbur Wilson

Harvey Weinstein

Executive Producer

Bob Weinstein

Executive Producer

Jessica Alba

Marissa Wilson

Angela Lanza

Female OSS Agent

Robert Rodriguez

Writer

Jonathan Breck

Wilbur's Boss

Rowan Blanchard

Rebecca Wilson

Mason Cook

Cecil Wilson

Chad Guerrero

Henchman in Van

Marci Madison

Agent Fine

Belle Solorzano

Spy Baby

Genny Solorzano

Spy Baby

Elmo

Argonaut

Jett Good

Young Danger

Chuck Cureau

News Anchor

Albert Im

Head Scientist

Wray Crawford

Editor / Cameraman

Alcides Dias

OSS Agent #1

Roger Edwards

OSS Agent #2