Angelina Jolie

Amelia Donaghy

Luis Guzmán

Eddie Ortiz

Queen Latifah

Thelma

Michael Rooker

Captain Howard Cheney

Larry Day

Gas Worker

Ed O'Neill

Detective Paulie Sellitto

Bobby Cannavale

Steve, Amelia's Boyfriend

Frank Fontaine

Grandfather

Denzel Washington

Lincoln Rhyme

Leland Orser

Richard Thompson

Desmond Campbell

Taxi Inspector

Michael McGlone

Detective Kenny Solomon

Richard Zeman

Lieutenant Carl Hanson

John Benjamin Hickey

Dr. Barry Lehman

Olivia Birkelund

Lindsay Rubin

Zena Grey

Granddaughter

Steve Adams

Gas Worker

Phillip Noyce

Director

Gary Swanson

Alan Rubin

James Bulleit

Train Engineer

Daniel Brochu

NYU Student

Christian Veliz

Young Boy

Mercedes Gómez

Ortiz's Mother

Mary C. Hammett

Girlfriend in Nightclub

Amanda Gay

Girl in Nightclub

Michael Klawitter

Executive Producer

Dan Jinks

Executive Producer