David Cross

Ian

Zachary Levi

Toby

Jason Lee

Dave

Justin Long

Alvin (voice)

Matthew Gray Gubler

Simon (voice)

Jesse McCartney

Theodore (voice)

Karen Rosenfelt

Executive Producer

Arnon Milchan

Executive Producer

Michele Imperato Stabile

Executive Producer

Steve Waterman

Executive Producer

Amy Poehler

Eleanor (voice)

Anna Faris

Jeanette (voice)

Christina Applegate

Brittany (voice)

Wendie Malick

Dr. Rubin

Anjelah Johnson-Reyes

Julie

Kathryn Joosten

Aunt Jackie

Kevin G. Schmidt

Ryan

Chris Warren

Xander

Bridgit Mendler

Becca

Aimee Carrero

Emily

Alexandra Shipp

Valentina

Gregg Binkley

Emcee

Jake Zyrus

Charice Pempengco

Bernard White

Doctor

Adele Jacques

Nurse

Joy Osmanski

Airline Rep

Archie Hahn

Agent

Lanny Joon

Paramedic

Betty Thomas

Director

Glenn Berger

Writer

Jonathan Aibel

Writer

Jon Vitti

Writer