Nicolas Cage

Frank Pierce

Ving Rhames

Marcus

John Goodman

Larry Verber

Queen Latifah

Dispatcher Love (voice)

Michael Kenneth Williams

Drug Dealer

Adam Schroeder

Executive Producer

Martin Scorsese

Dispatcher (voice)

Marc Anthony

Noel

Larry Fessenden

Cokehead

Cliff Curtis

Cy Coates

Tom Sizemore

Tom Wolls

Patricia Arquette

Mary Burke

Nestor Serrano

Dr. Hazmat

Arthur J. Nascarella

Captain Barney

Aida Turturro

Nurse Crupp

Mary Beth Hurt

Nurse Constance

Cynthia Roman

Rose

Sonja Sohn

Kanita

Craig muMs Grant

Voice in Crowd

John Heffernan

Mr. Oh

Judy Reyes

ICU Nurse

Afemo Omilami

Griss

Cullen O. Johnson

Mr. Burke

Julyana Soelistyo

Sister Fetus

Graciela Lecube

Neighbor Woman

Bruce S. Pustin

Executive Producer