Ossie Davis

Archer Dolittle

Eddie Murphy

Dr. John Dolittle

Garry Shandling

Male Pigeon (voice)

John Leguizamo

Rat #2 (Voice)

Raven-Symoné

Charisse

Chris Rock

Rodney (voice)

Julie Kavner

Female Pigeon (voice)

Albert Brooks

Tiger (voice)

Betty Thomas

Director

Jeffrey Tambor

Dr. Fish

Peter Boyle

Calloway

Oliver Platt

Dr. Mark Weller

Paul Reubens

Raccoon (voice)

Ellen DeGeneres

Prologue Dog (voice)

Eddie Frierson

Skunk (voice)

June Christopher

Diane

Norm Macdonald

Lucky (voice)

Kyla Pratt

Maya

Richard Schiff

Dr. Gene Reiss

Steven Gilborn

Dr. Litvack

Kristen Wilson

Lisa

Erik Dellums

Jeremy

Cherie Franklin

Mrs. Parkus

Jenna Elfman

Owl (Voice)

Reni Santoni

Rat #1 (Voice)

Sue Baden-Powell

Executive Producer

Jenno Topping

Executive Producer