Steve Carell

Blue (voice)

Ryan Reynolds

Cal

George Clooney

Spaceman (voice)

John Krasinski

Dad / Marshmallow (voice)

Bobby Moynihan

Jeremy

Awkwafina

Bubble (voice)

Louis Gossett Jr.

Lewis (voice)

Alan Kim

Benjamin

Emily Blunt

Unicorn (voice)

Fiona Shaw

Grandmother

Bradley Cooper

Ice (voice)

John J. Kelly

Executive Producer

Liza Colón-Zayas

Janet

Phoebe Waller-Bridge

Blossom (voice)

Ed Herbstman

Deli Guy

Cailey Fleming

Bea

George Dewey

Executive Producer

Catharine Daddario

Bea’s Mom

Audrey Hoffman

Bea (Ages 3 & 5)

Laquet Sharnell Pringle

Receptionist

Barbara Andres

Woman Upstairs

Alexander Rivero

Custodian

Shauna Pinkett

Hospital Receptionist

Sa'Raya Paris Johnson

7 Year-Old Girl

Marta Siteiya Moipei

Coffee Shop Barista

David Weissmann

Young Jeremy

Kimberly Nelson LoCascio

Executive Producer