Michelle Pfeiffer

Melanie Parker

George Clooney

Jack Taylor

Michael Massee

Eddie Parker

Amanda Peet

Celia

Mae Whitman

Maggie Taylor, Jack's daughter

Robert Klein

Dr. Martin

Ellen Greene

Mrs. Elaine Lieberman

Alex D. Linz

Sammy Parker, Melanie's son

Bitty Schram

Marla

Anna Maria Horsford

Evelyn

George Martin

Mr. Smith Leland

Sheila Kelley

Kristen, Jack's ex-wife

Joe Grifasi

Manny Feldstein

Barry Kivel

Mr. Yates, Sr.

Charles Durning

Lew, Jack's boss

Jon Robin Baitz

Mr. Yates, Jr.

Pete Hamill

Frank Burroughs

Gregory Jbara

Freddy

Holland Taylor

Rita

Rachel York

Liza

Marianne Muellerleile

Ruta

Steven Jang

Vincent Wang

Samantha Cintrón

Rosa Lopez

Victor Truro

Sammy's Pediatrician

Michael Hoffman

Director

Kate Guinzburg

Executive Producer