Leslie Mann

Debbie

John Lithgow

Oliver

Albert Brooks

Larry

Billie Joe Armstrong

Billie Joe Armstrong

Paul Rudd

Pete

Robert Smigel

Barry

Paula Pell

Executive Producer

Lo Mutuc

Jodi

Jason Segel

Jason

Chris O'Dowd

Ronnie

Lena Dunham

Cat

Judd Apatow

Director

Megan Fox

Desi

Wyatt Russell

Flirty Hockey Player

Melissa McCarthy

Catherine

Michael Ian Black

Accountant

Maude Apatow

Sadie

Tom Yi

Charlotte's Teacher

Annie Mumolo

Barb

Iris Apatow

Charlotte

Graham Parker

Graham Parker

Lisa Darr

Clair

Tim Bagley

Dr. Pellegrino

Ava Sambora

Wendy

Megan Grano

School Playdate Parent

D.A. Sandoval

Older Pregnant Parent